Migraine overview
A migraine is a headache that can purpose intense throbbing suffering or a pulsing sensation, typically on one facet of the head. It's often accompanied with the aid of nausea, vomiting, and excessive sensitivity to mild and sound. Migraine assaults can closing for hours to days, and the discomfort can be so excessive that it interferes with your each day activities. For some people, a warning symptom viewed as an air of secrecy takes location until now than or with the headache. An air of secrecy can consist of visible disturbances, such as flashes of mild or blind spots, or different disturbances, such as tingling on one thing of the face or in an arm or leg and concern speaking.
My experience-Chronic migraine and central sensitization
Hi all! Chronic migraine ~10 years that has progressively worsened over the last 2 years (“status migranosus”/intractable”). I’ve more recently been experiencing symptoms of central sensitization, including scalp and facial allodynia, hyper-sensitization to triggers (especially weather changes), and treatment resistance. I’m not really looking for advice, but I wanted to share an article that I found helpful for anyone experiencing this who are trying to gain a better understanding of what’s happening to them:
Migraine, Allodynia, and Central Sensitization
Most interesting excerpt (to me) with a great analogy:
“Central Sensitization is a medical term used to describe the brain’s neurons becoming hyperexcitable. The central nervous system has become unnaturally sensitized due to ongoing stimulation. An easy way to describe it is that the neurons develop a “memory” of the pain signals that are present during a Migraine attack and it changes accordingly to make the pain signals travel more easily. Some of these changes are related to neurotransmitters that relay messages between cells, especially glutamate and GABA. When these changes have been occurring for a while, allodynia can result.
The fact is, the better the pain memory, the easier it is for those pain signals to travel from neuron to neuron to the brain. Think of it like the evolution of a highway:
200 years ago a cattle path had a few cows coming and going. One day the farmer decided to use the cattle path as a road to get his family to town. He used it as a road for some time, it developed characteristic wagon ruts and soon the neighbors were using the new road too because it was easier than their less used route. Eventually the wagon ruts became a dirt road and lot of people were using it. The more people that used it, the easier it became to drive on it. The road is paved so even more could use it to go back and forth, and it eventually becomes a highway. If no one stops it, things get busy enough and it will turn into a freeway with thousands of cars each day traveling at high speeds.
In the case of our brains and central sensitization, a freeway is a bad thing because it represents changes within the brain that have lowered our ability to abort the Migraine attack. We want lightly-used cattle paths instead.”
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